PhD scholarship in Extraction and utilization of brewers’ spent grain proteins

Tuesday 14 Dec 21

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Apply no later than 31 January 2022
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Would you like to start your career working on our new project GRAINPEP, which aims at providing fundamental knowledge that will enable an efficient extraction of proteins from Brewers’ Spent Grain (BSG) by the use of green technologies, followed by enzyme hydrolysis and recovery of peptides, and to obtain an understanding of the structure-function relationship of peptides and proteins? The project is a collaboration with Aalborg University and Norwegian Technical and Natural Sciences University (NTNU) in Norway.

This PhD position concerns extraction of proteins from BSG using green technologies, followed by enzymatic hydrolysis and evaluation of the techno-functional properties and oxidative stability of the peptides when evaluated in emulsions.

You will be associated with the Research group for Bioactives – Analysis and Application at DTU Food. Research on sustainable production of ingredients from food side-streams is one of the focus areas of the group.

Responsibilities and qualifications
During your PhD project you will produce BSG in our labs. Then you will extract the proteins using green technologies such as supercritical CO2 extraction followed by ultrafiltration and perform enzymatic hydrolysis to produce peptides. The hydrolysis process will be designed in collaboration with Aalborg University who will use bioinformatics and proteomics to predict which peptides embedded in BSG protein that have emulsifying properties. Subsequently, you will evaluate the emulsifying properties and antioxidative effects of the peptides when applied as emulsifiers in emulsion. You will also investigate the properties of the peptides at oil-water interfaces and their molecular self-assembly in bulk phases and interfaces. The self-assembly properties will be studied using advance scattering techniques (SANS and SAXS). The PhD study includes a research stay at NTNU in Norway.

During the PhD work you will

  • be responsible for your own research, supervised by experienced and engaged supervisors in a collaborative environment,
  • perform research and contribute with new knowledge within the fields of production of peptides with techno-functional properties from food side-streams and the relationship between their structure and function,
  • engage in collaboration with the other scientists in GRAINPEP,
  • contribute to co-supervision of students and other teaching activities.

You must have a two-year master's degree in Food Technology, Chemical Engineering, or a similar degree with an academic level equivalent to a two-year master's degree.

Furthermore, the ideal candidate has:

  • Knowledge of and experience with emulsifiers and emulsions (e.g. physical stability during storage)
  • Knowledge of and experience with enzymatic hydrolysis
  • Knowledge of and experience with protein extraction will be an advantage
  • Experience with HPLC and MS analysis of proteins
  • Good laboratory skills
  • Good collaboration and communication skills (written and oral English)
  • Structured and analytical working approach
  • Skills within statistical analyses of data and data management

Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see the DTU's rules for the PhD education.

Assessment
The assessment of the candidates will be made by Prof. Charlotte Jacobsen and research scientist Betül Yesiltas from the Bioactives research group. The assessment will be based on the qualification requirements listed above as well as the grades from MSc/BSc education.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years.

Expected starting date is 1st April 2022 or as soon as possible thereafter.

You can read more about career paths at DTU here.

Further information
Further information may be obtained from the principal supervisor, Prof. Charlotte Jacobsen, Tel. + 45 23 27 90 75, mail: chja@food.dtu.dk

You can read more about DTU Food at www.food.dtu.dk

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

Application procedure
Your complete online application must be submitted no later than 31 January 2022 (Danish time).

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma including official description of grading scale
  • It is important that you document in your Curriculum vitae that you fulfil the eligibility requirements mentioned above

You may apply prior to ob­tai­ning your master's degree but cannot begin before having received it.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

You can read more about DTU Food on www.food.dtu.dk/english/Service/About-the-institute

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DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,900 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.